6IS0
Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA
Summary for 6IS0
Entry DOI | 10.2210/pdb6is0/pdb |
Descriptor | PDX1 C-terminal-inhibiting factor 1, m7G-capped RNA, S-ADENOSYL-L-HOMOCYSTEINE, ... (7 entities in total) |
Functional Keywords | rna methylation, methyltransferase, m6a, n6-methyladenosine, transferase-rna complex, transferase/rna |
Biological source | Danio rerio (Zebrafish) More |
Total number of polymer chains | 2 |
Total formula weight | 60027.73 |
Authors | Hirano, S.,Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2018-11-15, release date: 2018-12-05, Last modification date: 2024-03-06) |
Primary citation | Akichika, S.,Hirano, S.,Shichino, Y.,Suzuki, T.,Nishimasu, H.,Ishitani, R.,Sugita, A.,Hirose, Y.,Iwasaki, S.,Nureki, O.,Suzuki, T. Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363:-, 2019 Cited by PubMed: 30467178DOI: 10.1126/science.aav0080 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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