6IPZ

Fyn SH3 domain R96W mutant, crystallized with 18-crown-6

Summary for 6IPZ

• Entry DOI: 10.2210/pdb6ipz/pdb
• Related: 3H0F
• Descriptor: Tyrosine-protein kinase Fyn, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE (3 entities in total)
• Functional Keywords: kinase, sh3 domain, 18-crown-6, crown ether, protein binding
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 8378.20

Authors

Arold, S.T.,Aljedani, S.S.,Shahul Hameed, U.F. (deposition date: 2018-11-05, release date: 2018-11-28, Last modification date: 2023-11-22)

• Primary citation: Aldehaiman, A.,Momin, A.A.,Restouin, A.,Wang, L.,Shi, X.,Aljedani, S.,Opi, S.,Lugari, A.,Shahul Hameed, U.F.,Ponchon, L.,Morelli, X.,Huang, M.,Dumas, C.,Collette, Y.,Arold, S.T.; Synergy and allostery in ligand binding by HIV-1 Nef.; Biochem.J., 478:1525-1545, 2021; PubMed: 33787846; DOI: 10.1042/BCJ20201002

Experimental method

X-RAY DIFFRACTION (1.576 Å)