6IPB
Crystal Structure of the Cofactor-binding Domain of the Human Phase II Drug Metabolism Enzyme UGT2B15
Summary for 6IPB
Entry DOI | 10.2210/pdb6ipb/pdb |
Descriptor | UDP-glucuronosyltransferase 2B15, L(+)-TARTARIC ACID, GLYCEROL, ... (4 entities in total) |
Functional Keywords | drug metabolism, ugt, glycosyltransferase, tartaric acid, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 86339.26 |
Authors | |
Primary citation | Zhang, L.,Zhu, L.,Qu, W.,Wu, F.,Hu, M.,Xie, W.,Liu, Z.,Wang, C. Insight into tartrate inhibition patterns in vitro and in vivo based on cocrystal structure with UDP-glucuronosyltransferase 2B15. Biochem. Pharmacol., 172:113753-113753, 2019 Cited by PubMed: 31837310DOI: 10.1016/j.bcp.2019.113753 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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