6INE

Crystal Structure of human ASH1L-MRG15 complex

Summary for 6INE

• Entry DOI: 10.2210/pdb6ine/pdb
• Descriptor: Histone-lysine N-methyltransferase ASH1L, Mortality factor 4-like protein 1, ZINC ION, ... (6 entities in total)
• Functional Keywords: complex, h3k36 methyltransferase, transferase, transferase-protein binding complex, transferase/protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 52353.84

Authors

Hou, P.,Huang, C.,Liu, C.P.,Yu, T.,Yin, Y.,Zhu, B.,Xu, R.M. (deposition date: 2018-10-25, release date: 2019-03-20, Last modification date: 2023-11-22)

• Primary citation: Hou, P.,Huang, C.,Liu, C.P.,Yang, N.,Yu, T.,Yin, Y.,Zhu, B.,Xu, R.M.; Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.; Structure, 27:837-, 2019; PubMed: 30827843; DOI: 10.1016/j.str.2019.01.015

Experimental method

X-RAY DIFFRACTION (2.6 Å)