6IL3

Crystal structure of the FLT3 kinase bound to a small molecule inhibitor

Summary for 6IL3

• Entry DOI: 10.2210/pdb6il3/pdb
• Descriptor: Receptor-type tyrosine-protein kinase FLT3, 7-methoxy-6-(1-methyl-1H-pyrazol-4-yl)-3-(pyridin-2-yl)imidazo[1,2-a]pyridine, PHOSPHATE ION, ... (7 entities in total)
• Functional Keywords: receptor tyrosine kinase type i inhibitor atp binding domain dfg-in, signaling protein, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 45199.97

Authors

Thomas, C.J. (deposition date: 2018-10-16, release date: 2018-12-12, Last modification date: 2024-03-27)

• Primary citation: Thomas, C.J.; Crystal structure of the FLT3 kinase bound to a small molecule inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)