6IJY

Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 8-oxo-dGTP determined using a crystal obtained under microgravity

Summary for 6IJY

• Entry DOI: 10.2210/pdb6ijy/pdb
• Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION, ... (5 entities in total)
• Functional Keywords: alpha-beta-alpha sandwich, hydrolase, dna damage, dna repair, dna replication
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 37313.43

Authors

Nakamura, T.,Yamagata, Y. (deposition date: 2018-10-12, release date: 2019-02-20, Last modification date: 2024-03-27)

• Primary citation: Nakamura, T.,Hirata, K.,Fujimiya, K.,Chirifu, M.,Arimori, T.,Tamada, T.,Ikemizu, S.,Yamagata, Y.; X-ray Structure Analysis of Human Oxidized Nucleotide Hydrolase MTH1 using Crystals Obtained under Microgravity.; Int. J. Microgravity Sci. Appl., 36:-, 2019; DOI: 10.15011//jasma.36.360103

Experimental method

X-RAY DIFFRACTION (1.04 Å)