6IBL
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST FORMOTEROL AND NANOBODY Nb80
Replaces: 6H7KSummary for 6IBL
Entry DOI | 10.2210/pdb6ibl/pdb |
Descriptor | Thioredoxin 1,Beta-1 adrenergic receptor, Camelid antibody fragment Nb80, ~{N}-[5-[(1~{R})-2-[[(2~{R})-1-(4-methoxyphenyl)propan-2-yl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide, ... (6 entities in total) |
Functional Keywords | beta1 adrenoceptor, activated, agonist, nanobody, immune system |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 4 |
Total formula weight | 123393.64 |
Authors | Warne, T.,Edwards, P.C.,Dore, A.S.,Leslie, A.G.W.,Tate, C.G. (deposition date: 2018-11-30, release date: 2019-01-09, Last modification date: 2024-01-24) |
Primary citation | Lee, Y.,Warne, T.,Nehme, R.,Pandey, S.,Dwivedi-Agnihotri, H.,Chaturvedi, M.,Edwards, P.C.,Garcia-Nafria, J.,Leslie, A.G.W.,Shukla, A.K.,Tate, C.G. Molecular basis of beta-arrestin coupling to formoterol-bound beta1-adrenoceptor. Nature, 583:862-866, 2020 Cited by PubMed: 32555462DOI: 10.1038/s41586-020-2419-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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