6IBD
The Phosphatase and C2 domains of Human SHIP1
Summary for 6IBD
Entry DOI | 10.2210/pdb6ibd/pdb |
Descriptor | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (2 entities in total) |
Functional Keywords | phosphatidylinositol phosphate phosphatase, alzheimer's disease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 52877.57 |
Authors | Bradshaw, W.J.,Williams, E.P.,Fernandez-Cid, A.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2018-11-29, release date: 2019-01-16, Last modification date: 2024-02-14) |
Primary citation | Bradshaw, W.J.,Kennedy, E.C.,Moreira, T.,Smith, L.A.,Chalk, R.,Katis, V.L.,Benesch, J.L.P.,Brennan, P.E.,Murphy, E.J.,Gileadi, O. Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024 Cited by PubMed: 38309262DOI: 10.1016/j.str.2024.01.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.48 Å) |
Structure validation
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