6IBB

Crystal structure of the rat isoform of the succinate receptor SUCNR1 (GPR91) in complex with a nanobody

Summary for 6IBB

• Entry DOI: 10.2210/pdb6ibb/pdb
• Descriptor: Succinate receptor 1, Nanobody6, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (7 entities in total)
• Functional Keywords: sucnr1 gpr91 gpcr g-protein coupled receptor nanobody succinate complex, membrane protein
• Biological source: Rattus norvegicus (Norway Rat); More
• Total number of polymer chains: 4
• Total formula weight: 116776.95

Authors

Haffke, M.,Jaakola, V.-P. (deposition date: 2018-11-29, release date: 2019-08-14, Last modification date: 2024-01-24)

• Primary citation: Haffke, M.,Fehlmann, D.,Rummel, G.,Boivineau, J.,Duckely, M.,Gommermann, N.,Cotesta, S.,Sirockin, F.,Freuler, F.,Littlewood-Evans, A.,Kaupmann, K.,Jaakola, V.P.; Structural basis of species-selective antagonist binding to the succinate receptor.; Nature, 574:581-585, 2019; PubMed: 31645725; DOI: 10.1038/s41586-019-1663-8

Experimental method

X-RAY DIFFRACTION (2.12 Å)