6IBB
Crystal structure of the rat isoform of the succinate receptor SUCNR1 (GPR91) in complex with a nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Succinate receptor 1 | polymer | 342 | 39842.8 | 2 | UniProt (Q6IYF9) Pfam (PF00001) | Rattus norvegicus (Norway Rat) | G-protein coupled receptor 91 |
| 2 | B, D (B, D) | Nanobody6 | polymer | 142 | 15527.1 | 2 | Vicugna pacos (Alpaca) | ||
| 3 | E, F, G, H, I... (A, C) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 15 | Chemie (OLC) PubChem (25021708) PubChem (54294270) PubChem (46840179) PubChem (33022) PubChem (54294271) PubChem (5283468) PubChem (5364833) PubChem (11451146) PubChem (12178130) | |||
| 4 | M, W (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 5 | N (A) | (2~{S},5~{R})-hexane-2,5-diol | non-polymer | 118.2 | 1 | Chemie (H95) | |||
| 6 | Q (C) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) PubChem (16219173) PubChem (16758052) PubChem (176980071) PubChem (18640088) PubChem (1715243) PubChem (1715244) PubChem (23423981) PubChem (44654663) PubChem (46937002) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (59274407) PubChem (45044259) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (5997) PubChem (1551269) PubChem (90070115) PubChem (49853509) PubChem (50990013) PubChem (117965027) PubChem (6432564) PubChem (6710666) PubChem (124146240) PubChem (52934537) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (10861996) PubChem (56621683) PubChem (132837164) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (138967089) PubChem (139566851) PubChem (15939944) PubChem (57915018) PubChem (57939063) PubChem (58428240) PubChem (58445498) PubChem (58663286) PubChem (171828367) PubChem (173516975) PubChem (59450329) PubChem (59628412) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (89951918) PubChem (90224410) PubChem (91298236) PubChem (101624109) PubChem (304) PubChem (124225449) PubChem (191463) PubChem (368063) PubChem (369319) PubChem (124429284) PubChem (638019) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (1549081) PubChem (1553803) PubChem (5283629) PubChem (5284644) PubChem (5315842) PubChem (6419195) PubChem (6994560) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (11463329) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (130459183) PubChem (12120344) PubChem (12156156) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (131992107) PubChem (139568882) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) | |||
| 7 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence modifications
A, C: 2 - 317 (UniProt: Q6IYF9)
| PDB | External Database | Details |
|---|---|---|
| Asp -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Lys -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Lys 1 | - | expression tag |
| Leu 318 | - | expression tag |
| Glu 319 | - | expression tag |
| Val 320 | - | expression tag |
| Leu 321 | - | expression tag |
| Phe 322 | - | expression tag |
| Gln 323 | - | expression tag |
| Gly 324 | - | expression tag |
| Pro 325 | - | expression tag |
| His 326 | - | expression tag |
| His 327 | - | expression tag |
| His 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| His 333 | - | expression tag |
| His 334 | - | expression tag |
| His 335 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 110739.8 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 6037.1 | |
| All* | Total formula weight | 116777.0 |
