6I9N
JmjC domain-containing protein 5 (JMJD5) in complex with Mn and L-2-hydroxyglutarate
Summary for 6I9N
Entry DOI | 10.2210/pdb6i9n/pdb |
Descriptor | JmjC domain-containing protein 5, MANGANESE (II) ION, (2S)-2-HYDROXYPENTANEDIOIC ACID, ... (6 entities in total) |
Functional Keywords | oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, jmjc, jmjc domain, lysine-specific demethylase 8, jmjc domain-containing protein 5, arginyl c-3 hydroxylase, jmjd5, kdm8, oxygenase, hypoxia, dna-binding, metal-binding, translation, dsbh, facial triad, cytoplasm, jmjc hydroxylase, jmjc demethylase, kdms, post-translational modifications, ptm, beta-hydroxylation, hydroxylation, arginine hydroxylation, rcc1 domain-containing protein 1, rccd1, regulator of chromosome condensation, 40s ribosomal protein s6, rps6, ribosome biogenesis, transcription, epigenetic regulation, signaling, development, cell structure, transcription activator/inhibitor, phosphorylation, cancer, polymorphism |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 30150.84 |
Authors | Chowdhury, R.,Islam, M.S.,Schofield, C.J. (deposition date: 2018-11-24, release date: 2019-12-04, Last modification date: 2024-01-31) |
Primary citation | Islam, M.S.,Markoulides, M.,Chowdhury, R.,Schofield, C.J. Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5. Sci Rep, 12:20680-20680, 2022 Cited by PubMed: 36450832DOI: 10.1038/s41598-022-24154-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.361 Å) |
Structure validation
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