6I6X
New Irreversible a-l-Iduronidase Inhibitors and Activity-Based Probes
Summary for 6I6X
Entry DOI | 10.2210/pdb6i6x/pdb |
Related | 6I6R |
Descriptor | Alpha-L-iduronidase, CHLORIDE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | iduronidase inhibitors gh39, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 145017.02 |
Authors | Gloster, T.M.,McMahon, S.A.,Oehler, V. (deposition date: 2018-11-15, release date: 2018-12-05, Last modification date: 2024-01-24) |
Primary citation | Artola, M.,Kuo, C.L.,McMahon, S.A.,Oehler, V.,Hansen, T.,van der Lienden, M.,He, X.,van den Elst, H.,Florea, B.I.,Kermode, A.R.,van der Marel, G.A.,Gloster, T.M.,Codee, J.D.C.,Overkleeft, H.S.,Aerts, J.M.F.G. New Irreversible alpha-l-Iduronidase Inhibitors and Activity-Based Probes. Chemistry, 24:19081-19088, 2018 Cited by PubMed: 30307091DOI: 10.1002/chem.201804662 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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