6I3C

Crystal structure of Human soluble catechol O-methyltransferase in complex with 3,5-dinitrocatechol and S-adensoyl-L-methionine

Summary for 6I3C

• Entry DOI: 10.2210/pdb6i3c/pdb
• Descriptor: Catechol O-methyltransferase, MAGNESIUM ION, S-ADENOSYLMETHIONINE, ... (5 entities in total)
• Functional Keywords: enzyme, s-adenosyl-l-methionine, catechol o-methyltransferase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 26593.47

Authors

Levy, C.W. (deposition date: 2018-11-05, release date: 2019-09-18)

• Primary citation: Czarnota, S.,Johannissen, L.O.,Baxter, N.J.,Rummel, F.,Wilson, A.L.,Cliff, M.J.,Levy, C.W.,Scrutton, N.S.,Waltho, J.P.,Hay, S.; Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase.; Acs Catalysis, 9:4394-4401, 2019; PubMed: 31080692; DOI: 10.1021/acscatal.9b00174

Experimental method

X-RAY DIFFRACTION (1.336 Å)