6I2Y
Human STK10 bound to Foretinib
Summary for 6I2Y
Entry DOI | 10.2210/pdb6i2y/pdb |
Descriptor | Serine/threonine-protein kinase 10, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (2 entities in total) |
Functional Keywords | kinase, inhibitor, complex, lok, transferase, foretinib |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 69746.32 |
Authors | Sorrell, F.J.,Berger, B.-T.,Oerum, S.,von Delft, F.,Bountra, C.,Arrowsmith, C.,Edwards, A.M.,Knapp, S.,Elkins, J.M. (deposition date: 2018-11-02, release date: 2018-12-12) |
Primary citation | Sorrell, F.J.,Elkins, J.M. Human STK10 bound to GW683134 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.56 Å) |
Structure validation
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