6I2Y
Human STK10 bound to Foretinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase 10 | polymer | 302 | 34240.5 | 2 | UniProt (O94804) Pfam (PF00069) | Homo sapiens (Human) | Lymphocyte-oriented kinase |
| 2 | C, D (A, B) | N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | non-polymer | 632.7 | 2 | Chemie (88Z) |
Sequence modifications
A, B: 18 - 317 (UniProt: O94804)
| PDB | External Database | Details |
|---|---|---|
| Ser 16 | - | expression tag |
| Met 17 | - | expression tag |
| Ala 272 | Lys 272 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68481.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1265.3 | |
| All* | Total formula weight | 69746.3 |
