6I2D

Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus Griseus in complex with compounds RKp182 and RKp117

6EMD」から置き換えられました

6I2D の概要

分子名称cAMP-dependent protein kinase catalytic subunit alpha, UPF0418 protein FAM164A, [2-[(4-isoquinolin-5-ylsulfonyl-1,4-diazepan-1-yl)methyl]phenyl]boronic acid, ... (4 entities in total)
機能のキーワードcomplex, peptidic ligand, transferase
由来する生物種Cricetulus griseus (Chinese hamster)
ポリマー鎖数2
分子量合計43623.24
構造登録者
Mueller, J.M.,Heine, A.,Klebe, G. (登録日: 2018-11-01, 公開日: 2019-05-15)
主引用文献
Mueller, J.M.,Kirschner, R.,Geyer, A.,Klebe, G.
Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage
Acs Omega, 2019
DOI: 10.1021/acsomega.8b02364
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.91 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22310 0.4% 0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード

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