6HOH

Structure of VPS34 LIR motif (S249E) bound to GABARAP

6HOH の概要

• エントリーDOI: 10.2210/pdb6hoh/pdb
• 分子名称: Phosphatidylinositol 3-kinase catalytic subunit type 3,Gamma-aminobutyric acid receptor-associated protein, TRIETHYLENE GLYCOL (3 entities in total)
• 機能のキーワード: autophagy, atg8, lir, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 61084.25

構造登録者

Mouilleron, S.,Birgisdottir, A.B.,Bhujbal, Z.,Wirth, M.,Sjottem, E.,Evjen, G.,Zhang, W.,Lee, R.,O'Reilly, N.,Tooze, S.,Lamark, T.,Johansen, T. (登録日: 2018-09-17, 公開日: 2019-02-27, 最終更新日: 2024-01-24)

• 主引用文献: Birgisdottir, A.B.,Mouilleron, S.,Bhujabal, Z.,Wirth, M.,Sjottem, E.,Evjen, G.,Zhang, W.,Lee, R.,O'Reilly, N.,Tooze, S.A.,Lamark, T.,Johansen, T.; Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.; Autophagy, 15:1333-1355, 2019; PubMed: 30767700; DOI: 10.1080/15548627.2019.1581009

実験手法

X-RAY DIFFRACTION (2.25 Å)