6HIL

X-ray structure of TEAD1(Y421H mutant) complexed with YAP(wildtype): Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy

Summary for 6HIL

• Entry DOI: 10.2210/pdb6hil/pdb
• Related: 6HIK
• Descriptor: Transcriptional enhancer factor TEF-1, Transcriptional coactivator YAP1, MYRISTIC ACID, ... (4 entities in total)
• Functional Keywords: other, transcription factor, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 120409.68

Authors

Kallen, J. (deposition date: 2018-08-30, release date: 2019-04-03, Last modification date: 2024-01-17)

• Primary citation: Bokhovchuk, F.,Mesrouze, Y.,Izaac, A.,Meyerhofer, M.,Zimmermann, C.,Fontana, P.,Schmelzle, T.,Erdmann, D.,Furet, P.,Kallen, J.,Chene, P.; Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy.; Febs J., 286:2381-2398, 2019; PubMed: 30903741; DOI: 10.1111/febs.14817

Experimental method

X-RAY DIFFRACTION (2.3 Å)