6HG5

Influenza A virus N6 neuraminidase complex with Oseltamivir (Duck/England/56).

Summary for 6HG5

DescriptorNeuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... (9 entities in total)
Functional Keywordsinfluenza, a, oseltamivir, n6, neuraminidase, duck, virus, enzyme, inhibitor, complex, hydrolase, gs4071, tamiflu
Biological sourceInfluenza A virus (strain A/Duck/England/1/1956 H11N6)
Total number of polymer chains4
Total molecular weight181662.46
Authors
Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F. (deposition date: 2018-08-22, release date: 2018-08-29, Last modification date: 2018-09-05)
Primary citation
Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F.
High Resolution Structures of Viral Neuraminidase with Drugs Bound in the Active Site.
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.168600.6%0.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report