6HC8
Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPA1 (313-339)
Summary for 6HC8
Entry DOI | 10.2210/pdb6hc8/pdb |
Descriptor | Hypoxia-inducible factor 1-alpha inhibitor, Transient receptor potential cation channel subfamily A member 1, ZINC ION, ... (7 entities in total) |
Functional Keywords | non-heme, dioxygenase, oxygenase, metal-binding, transcription, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, signaling, ard, beta-hydroxylation, activator-inhibitor, oxidoreductase-peptide complex, oxidoreductase ankyrin, channel, protein binding, ion channel, trpa channel, membrane protein, gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 44068.62 |
Authors | Leissing, T.M.,Clifton, I.J.,Saward, B.G.,Lu, X.,Hopkinson, R.J.,Schofield, C.J. (deposition date: 2018-08-14, release date: 2019-08-28, Last modification date: 2024-01-17) |
Primary citation | Leissing, T.M.,Clifton, I.J.,Saward, B.G.,Lu, X.,Hopkinson, R.J.,Schofield, C.J. Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPA1 (313-339) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report