6HC8
Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPA1 (313-339)
6HC8 の概要
エントリーDOI | 10.2210/pdb6hc8/pdb |
分子名称 | Hypoxia-inducible factor 1-alpha inhibitor, Transient receptor potential cation channel subfamily A member 1, ZINC ION, ... (7 entities in total) |
機能のキーワード | non-heme, dioxygenase, oxygenase, metal-binding, transcription, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, signaling, ard, beta-hydroxylation, activator-inhibitor, oxidoreductase-peptide complex, oxidoreductase ankyrin, channel, protein binding, ion channel, trpa channel, membrane protein, gene regulation |
由来する生物種 | Homo sapiens (Human) 詳細 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 44068.62 |
構造登録者 | Leissing, T.M.,Clifton, I.J.,Saward, B.G.,Lu, X.,Hopkinson, R.J.,Schofield, C.J. (登録日: 2018-08-14, 公開日: 2019-08-28, 最終更新日: 2024-01-17) |
主引用文献 | Leissing, T.M.,Clifton, I.J.,Saward, B.G.,Lu, X.,Hopkinson, R.J.,Schofield, C.J. Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPA1 (313-339) To Be Published, |
実験手法 | X-RAY DIFFRACTION (1.9 Å) |
構造検証レポート
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