6HC3

TFAM bound to Site-X

Summary for 6HC3

• Entry DOI: 10.2210/pdb6hc3/pdb
• Descriptor: Transcription factor A, mitochondrial, DNA/RNA (5'-D(*TP*AP*AP*CP*AP*AP*AP*AP*AP*AP*TP*TP*TP*CP*CP*AP*CP*CP*AP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*TP*GP*GP*TP*GP*GP*AP*AP*AP*TP*TP*TP*TP*TP*TP*GP*TP*TP*AP*G)-3'), ... (6 entities in total)
• Functional Keywords: transcription factor, dna compaction, mitochondria, mitochondrial dna, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 163671.17

Authors

Fernandez-Millan, P.,Cuppari, A.,Tarres-Sole, A.,Rubio-Cosials, A.,Lyonnais, S.,Sola, M. (deposition date: 2018-08-13, release date: 2019-06-05, Last modification date: 2024-01-17)

• Primary citation: Cuppari, A.,Fernandez-Millan, P.,Battistini, F.,Tarres-Sole, A.,Lyonnais, S.,Iruela, G.,Ruiz-Lopez, E.,Enciso, Y.,Rubio-Cosials, A.,Prohens, R.,Pons, M.,Alfonso, C.,Toth, K.,Rivas, G.,Orozco, M.,Sola, M.; DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region.; Nucleic Acids Res., 47:6519-6537, 2019; PubMed: 31114891; DOI: 10.1093/nar/gkz406

Experimental method

X-RAY DIFFRACTION (3.1 Å)