6HC3
TFAM bound to Site-X
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue TLA A 301 |
| Chain | Residue |
| A | TLA302 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue TLA A 302 |
| Chain | Residue |
| A | ASN191 |
| A | LEU192 |
| A | TLA301 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue TLA A 303 |
| Chain | Residue |
| A | GLY153 |
| A | GLU214 |
| A | TRP218 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE A 304 |
| Chain | Residue |
| A | LEU129 |
| A | GLU130 |
| A | TYR110 |
| A | LYS118 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue TLA D 301 |
| Chain | Residue |
| D | LEU151 |
| D | LEU152 |
| D | GLN221 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue 1PE D 302 |
| Chain | Residue |
| D | TYR110 |
| D | LYS118 |
| D | LEU129 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue TLA G 301 |
| Chain | Residue |
| G | LEU151 |
| G | GLN221 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue 1PE G 302 |
| Chain | Residue |
| G | TYR110 |
| G | LYS118 |
| G | LEU129 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue 1PE J 301 |
| Chain | Residue |
| J | CYS49 |
| J | LYS118 |
| J | LEU129 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 272 |
| Details | DNA binding: {"description":"HMG box 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00267","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 256 |
| Details | DNA binding: {"description":"HMG box 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00267","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Site: {"description":"Intercalates between bases and promotes DNA bending"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | Modified residue: {"description":"Phosphoserine; by PKA","evidences":[{"source":"PubMed","id":"23201127","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
