Crystal structure of the BiP NBD and MANF complex

Summary for 6HA7

DescriptorEndoplasmic reticulum chaperone BiP, Mesencephalic astrocyte-derived neurotrophic factor, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsmanf, bip, nbd, ndi, armet, hsp70, chaperone
Biological sourceCricetulus griseus (Chinese hamster)
Total number of polymer chains4
Total molecular weight121862.7
Yan, Y.,Ron, D. (deposition date: 2018-08-07, release date: 2019-02-06, Last modification date: 2019-02-13)
Primary citation
Yan, Y.,Rato, C.,Rohland, L.,Preissler, S.,Ron, D.
MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP.
Nat Commun, 10:541-541, 2019
PubMed: 30710085 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-019-08450-4
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26210 0.5% 1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6ha7
no rotation
Molmil generated image of 6ha7
rotated about x axis by 90°
Molmil generated image of 6ha7
rotated about y axis by 90°
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