6H1E
Crystal structure of C21orf127-TRMT112 in complex with SAH and H4 peptide
Summary for 6H1E
Entry DOI | 10.2210/pdb6h1e/pdb |
Descriptor | HemK methyltransferase family member 2, Multifunctional methyltransferase subunit TRM112-like protein, Histone H4 peptide, ... (5 entities in total) |
Functional Keywords | protein methyltransferase, histone methylation, complex, sah, gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 39114.99 |
Authors | Wang, S.,Hermann, B.,Metzger, E.,Peng, L.,Einsle, O.,Schuele, R. (deposition date: 2018-07-11, release date: 2019-05-22, Last modification date: 2024-01-17) |
Primary citation | Metzger, E.,Wang, S.,Urban, S.,Willmann, D.,Schmidt, A.,Offermann, A.,Allen, A.,Sum, M.,Obier, N.,Cottard, F.,Ulferts, S.,Preca, B.T.,Hermann, B.,Maurer, J.,Greschik, H.,Hornung, V.,Einsle, O.,Perner, S.,Imhof, A.,Jung, M.,Schule, R. KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells. Nat.Struct.Mol.Biol., 26:361-371, 2019 Cited by PubMed: 31061526DOI: 10.1038/s41594-019-0219-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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