6H03

OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX

This is a large structure.

Summary for 6H03

Related6H04
EMDB information0106 0107 0109 0111 0112 0113 0110
DescriptorComplement C5,Complement C5, Complement component C8 beta chain, Complement component C7, ... (9 entities in total)
Functional Keywordsc5b9, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains24
Total molecular weight1631460.42
Authors
Menny, A.,Serna, M.,Boyd, C.M.,Gardner, S.,Joseph, A.P.,Topf, M.,Bubeck, D. (deposition date: 2018-07-06, release date: 2018-12-19, Last modification date: 2018-12-26)
Primary citation
Menny, A.,Serna, M.,Boyd, C.M.,Gardner, S.,Joseph, A.P.,Morgan, B.P.,Topf, M.,Brooks, N.J.,Bubeck, D.
CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9:5316-5316, 2018
PubMed: 30552328 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-07653-5
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (5.6 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers21 0.0% 3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 6h03
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Molmil generated image of 6h03
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Molmil generated image of 6h03
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