6GTU

17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with fragment J6

Summary for 6GTU

• Entry DOI: 10.2210/pdb6gtu/pdb
• Related: 6EMM 6GTB
• Descriptor: 17-beta-hydroxysteroid dehydrogenase 14, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, N-(1,3-benzodioxol-5-ylmethyl)cyclopentanamine, ... (6 entities in total)
• Functional Keywords: fragments, soaking, 17b-hsd14, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 29751.07

Authors

Bertoletti, N.,Heine, A.,Marchais-Oberwinkler, S.,Klebe, G. (deposition date: 2018-06-19, release date: 2019-07-03, Last modification date: 2024-01-17)

• Primary citation: Bertoletti, N.,Braun, F.,Zara, L.,Metz, A.,Heine, A.,Marchais-Oberwinkler, S.,Klebe, G.; X-ray Crystallographic Fragment screening and Hit Optimization; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)