6GPR

Structure of human Heat shock protein 90-alpha N-terminal domain (Hsp90-NTD) in complex with cAMP

Summary for 6GPR

• Entry DOI: 10.2210/pdb6gpr/pdb
• Related: 6GP4
• Descriptor: Heat shock protein HSP 90-alpha, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
• Functional Keywords: chaperone, hsp90, ntd, alpha
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 29102.35

Authors

Tassone, G.,Pozzi, C.,Mangani, S.,Botta, M. (deposition date: 2018-06-06, release date: 2018-10-03, Last modification date: 2024-01-17)

• Primary citation: Tassone, G.,Mangani, S.,Botta, M.,Pozzi, C.; Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart.; Biochim Biophys Acta Proteins Proteom, 1866:1190-1198, 2018; PubMed: 30248409; DOI: 10.1016/j.bbapap.2018.09.005

Experimental method

X-RAY DIFFRACTION (2.35 Å)