6GO6
TdT chimera (Loop1 of pol mu) - ternary complex with downstream dsDNA
Summary for 6GO6
Entry DOI | 10.2210/pdb6go6/pdb |
Descriptor | DNA nucleotidylexotransferase,DNA-directed DNA/RNA polymerase mu,DNA nucleotidylexotransferase, DNA (5'-D(*TP*TP*TP*TP*TP*GP*GP*C)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*C)-3'), ... (7 entities in total) |
Functional Keywords | nhej pathway, dna bridging, dna polymerase polx, dna binding protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 53004.89 |
Authors | Loc'h, J.,Gerodimos, C.A.,Rosario, S.,Lieber, M.R.,Delarue, M. (deposition date: 2018-06-01, release date: 2019-06-05, Last modification date: 2024-01-17) |
Primary citation | Loc'h, J.,Gerodimos, C.A.,Rosario, S.,Tekpinar, M.,Lieber, M.R.,Delarue, M. Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction. J.Biol.Chem., 294:10579-10595, 2019 Cited by PubMed: 31138645DOI: 10.1074/jbc.RA119.008739 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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