6GLC
Structure of phospho-Parkin bound to phospho-ubiquitin
Summary for 6GLC
Entry DOI | 10.2210/pdb6glc/pdb |
Descriptor | E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION, ... (7 entities in total) |
Functional Keywords | ubiquitin, parkin, phospho-ubiquitin, parkinson's disease, e3 ligase, rbr domain, mitophagy, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 52532.38 |
Authors | Gladkova, C.,Maslen, S.L.,Skehel, J.M.,Komander, D. (deposition date: 2018-05-23, release date: 2018-06-13, Last modification date: 2024-01-17) |
Primary citation | Gladkova, C.,Maslen, S.L.,Skehel, J.M.,Komander, D. Mechanism of parkin activation by PINK1. Nature, 559:410-414, 2018 Cited by PubMed: 29995846DOI: 10.1038/s41586-018-0224-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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