6GKZ

Crystal structure of Coclaurine N-Methyltransferase (CNMT) bound to N-methylheliamine and SAH

Summary for 6GKZ

• Entry DOI: 10.2210/pdb6gkz/pdb
• Related: 6GKV 6GKY
• Descriptor: Coclaurine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• Functional Keywords: n-methylheliamine, coclaurine n-methyltransferase, transferase
• Biological source: Coptis japonica (Japanese goldthread)
• Total number of polymer chains: 4
• Total formula weight: 167884.22

Authors

Dunstan, M.S.,Levy, C.W. (deposition date: 2018-05-22, release date: 2019-01-16)

• Primary citation: Bennett, M.R.,Thompson, M.L.,Shepherd, S.A.,Dunstan, M.S.,Herbert, A.J.,Smith, D.R.M.,Cronin, V.A.,Menon, B.R.K.,Levy, C.,Micklefield, J.; Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase.; Angew. Chem. Int. Ed. Engl., 57:10600-10604, 2018; PubMed: 29791083; DOI: 10.1002/anie.201805060

Experimental method

X-RAY DIFFRACTION (2.43 Å)