6GKY
Crystal structure of Coclaurine N-Methyltransferase (CNMT) bound to N-methylheliamine and SAH
Summary for 6GKY
| Entry DOI | 10.2210/pdb6gky/pdb |
| Related | 6GKV |
| Descriptor | Coclaurine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 6,7-dimethoxy-2,4-dihydro-1~{H}-isoquinolin-3-one (3 entities in total) |
| Functional Keywords | n-methylheliamine, coclaurine n-methyltransferase, transferase |
| Biological source | Coptis japonica (Japanese goldthread) |
| Total number of polymer chains | 2 |
| Total formula weight | 83324.88 |
| Authors | Dunstan, M.S.,Levy, C.W. (deposition date: 2018-05-22, release date: 2018-06-06, Last modification date: 2018-08-29) |
| Primary citation | Bennett, M.R.,Thompson, M.L.,Shepherd, S.A.,Dunstan, M.S.,Herbert, A.J.,Smith, D.R.M.,Cronin, V.A.,Menon, B.R.K.,Levy, C.,Micklefield, J. Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase. Angew. Chem. Int. Ed. Engl., 57:10600-10604, 2018 Cited by PubMed: 29791083DOI: 10.1002/anie.201805060 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.847 Å) |
Structure validation
Download full validation report
