6GJK

A degradation product of PD 404182 (P2742) bound to Histone Deacetylase-like Amidohydrolase

6GJK の概要

• エントリーDOI: 10.2210/pdb6gjk/pdb
• 分子名称: Histone deacetylase-like amidohydrolase, ZINC ION, POTASSIUM ION, ... (9 entities in total)
• 機能のキーワード: hdah, hdac, p2742, pd 404182, histone deacetylase-like amidohydrolase, histone deacetylase, covalent modification, hydrolase
• 由来する生物種: Alcaligenaceae bacterium FB188
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 82928.75

構造登録者

Kraemer, A.,Meyer-Almes, F.J. (登録日: 2018-05-16, 公開日: 2019-01-16, 最終更新日: 2024-01-17)

• 主引用文献: Muth, M.,Jansch, N.,Kopranovic, A.,Kramer, A.,Wossner, N.,Jung, M.,Kirschhofer, F.,Meyer-Almes, F.J.; Covalent inhibition of histone deacetylase 8 by 3,4-dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine.; Biochim Biophys Acta Gen Subj, 1863:577-585, 2019; PubMed: 30611847; DOI: 10.1016/j.bbagen.2019.01.001

実験手法

X-RAY DIFFRACTION (1.47 Å)