6GEG
TEAD4 (216-434);Y429F COMPLEXED WITH YAP PEPTIDE (60-100); S94A AND MYRISTOATE (COVALENTLY BOUND) AT 2.23A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA
6GEG の概要
エントリーDOI | 10.2210/pdb6geg/pdb |
関連するPDBエントリー | 6GE3 6GE4 6GE5 6GE6 6GEC 6GEE |
分子名称 | Transcriptional enhancer factor TEF-3, Transcriptional coactivator YAP1, MYRISTIC ACID, ... (4 entities in total) |
機能のキーワード | transcription, co-activator complex, protein-protein interaction |
由来する生物種 | Homo sapiens (Human) 詳細 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 30244.33 |
構造登録者 | |
主引用文献 | Mesrouze, Y.,Bokhovchuk, F.,Izaac, A.,Meyerhofer, M.,Zimmermann, C.,Fontana, P.,Schmelzle, T.,Erdmann, D.,Furet, P.,Kallen, J.,Chene, P. Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface. Protein Sci., 27:1810-1820, 2018 Cited by PubMed: 30058229DOI: 10.1002/pro.3493 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.23 Å) |
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