6GEG
TEAD4 (216-434);Y429F COMPLEXED WITH YAP PEPTIDE (60-100); S94A AND MYRISTOATE (COVALENTLY BOUND) AT 2.23A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcriptional enhancer factor TEF-3 | polymer | 219 | 25484.7 | 1 | UniProt (Q15561) Pfam (PF17725) | Homo sapiens (Human) | TEA domain family member 4,TEAD-4,Transcription factor 13-like 1,Transcription factor RTEF-1 |
| 2 | B (L) | Transcriptional coactivator YAP1 | polymer | 41 | 4531.2 | 1 | UniProt (P46937) Pfam (PF15238) | Homo sapiens | Yes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog |
| 3 | C (A) | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
| 4 | D, E (A, L) | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A: 216 - 434 (UniProt: Q15561)
L: 60 - 99 (UniProt: P46937)
| PDB | External Database | Details |
|---|---|---|
| Phe 429 | Tyr 429 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ace 59 | - | expression tag |
| Ala 94 | Ser 94 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30016.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 228.4 | |
| All* | Total formula weight | 30244.3 |
