6GDY

Crystal structure of 2OG oxygenase JMJD6 (aa 1-343) in complex with Fe(II) and 2OG

6GDY の概要

• エントリーDOI: 10.2210/pdb6gdy/pdb
• 分子名称: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, FE (III) ION, 2-OXOGLUTARIC ACID, ... (8 entities in total)
• 機能のキーワード: bi-functional 2og oxygenase, lysyl hydroxylase, arginine demethylase, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 82616.55

構造登録者

Islam, M.S.,Schofield, C.J.,McDonough, M.A. (登録日: 2018-04-24, 公開日: 2019-04-03, 最終更新日: 2024-05-15)

• 主引用文献: Islam, M.S.,McDonough, M.A.,Chowdhury, R.,Gault, J.,Khan, A.,Pires, E.,Schofield, C.J.; Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6.; J.Biol.Chem., 294:11637-11652, 2019; PubMed: 31147442; DOI: 10.1074/jbc.RA119.008693

実験手法

X-RAY DIFFRACTION (2.04 Å)