6GBK
Repertoires of functionally diverse enzymes through computational design at epistatic active-site positions
Summary for 6GBK
Entry DOI | 10.2210/pdb6gbk/pdb |
Descriptor | Parathion hydrolase, FORMIC ACID, ZINC ION, ... (5 entities in total) |
Functional Keywords | phosphotriesterase, hydrolase |
Biological source | Brevundimonas diminuta (Pseudomonas diminuta) |
Total number of polymer chains | 2 |
Total formula weight | 73408.05 |
Authors | Khersonsky, O.,Lipsh, R.,Avizemer, Z.,Goldsmith, M.,Ashani, Y.,Leader, H.,Dym, O.,Rogotner, S.,Trudeau, D.,Tawfik, D.S.,Fleishman, S.J. (deposition date: 2018-04-15, release date: 2018-10-24, Last modification date: 2024-01-17) |
Primary citation | Khersonsky, O.,Lipsh, R.,Avizemer, Z.,Ashani, Y.,Goldsmith, M.,Leader, H.,Dym, O.,Rogotner, S.,Trudeau, D.L.,Prilusky, J.,Amengual-Rigo, P.,Guallar, V.,Tawfik, D.S.,Fleishman, S.J. Automated Design of Efficient and Functionally Diverse Enzyme Repertoires. Mol. Cell, 72:178-186.e5, 2018 Cited by PubMed: 30270109DOI: 10.1016/j.molcel.2018.08.033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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