6G8K
14-3-3sigma in complex with a S131beta3S mutated YAP pS127 phosphopeptide
Summary for 6G8K
Entry DOI | 10.2210/pdb6g8k/pdb |
Related | 6g6x 6g8i 6g8j |
Descriptor | 14-3-3 protein sigma, ACE-ARG-ALA-HIS-SEP-SER-PRO-ALA-BSE-LEU-GLN, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | beta amino acid, hippo pathway, yap/taz, oncoprotein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 27836.30 |
Authors | Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. (deposition date: 2018-04-09, release date: 2019-04-17, Last modification date: 2024-01-17) |
Primary citation | Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. A study on the effect of synthetic alpha-to-beta3-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins. Chem.Commun.(Camb.), 55:14809-14812, 2019 Cited by PubMed: 31763628DOI: 10.1039/c9cc07982c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
Download full validation report