6G8F

Crystal structure of UTX complexed with GSK-J1

Summary for 6G8F

Entry DOI	10.2210/pdb6g8f/pdb
Descriptor	Lysine-specific demethylase 6A, MANGANESE (II) ION, ZINC ION, ... (7 entities in total)
Functional Keywords	jumonji demethylase, inhibitor, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	61122.16
Authors	Esposito, C.,Sledz, P.,Caflisch, A. (deposition date: 2018-04-08, release date: 2018-10-10, Last modification date: 2024-01-17)
Primary citation	Esposito, C.,Wiedmer, L.,Caflisch, A. In Silico Identification of JMJD3 Demethylase Inhibitors. J Chem Inf Model, 58:2151-2163, 2018 Cited by PubMed: 30226987 DOI: 10.1021/acs.jcim.8b00539 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.043 Å)

Structure validation