6G8F
Crystal structure of UTX complexed with GSK-J1
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 1501 |
| Chain | Residue |
| A | HIS1146 |
| A | GLU1148 |
| A | K0I1503 |
| A | HOH1623 |
| A | HOH1690 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1502 |
| Chain | Residue |
| A | CYS1331 |
| A | CYS1334 |
| A | CYS1358 |
| A | CYS1361 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue K0I A 1503 |
| Chain | Residue |
| A | ARG1001 |
| A | GLN1003 |
| A | SER1025 |
| A | THR1086 |
| A | ASN1087 |
| A | TYR1135 |
| A | LYS1137 |
| A | ARG1142 |
| A | THR1143 |
| A | PRO1144 |
| A | HIS1146 |
| A | GLU1148 |
| A | ASN1149 |
| A | ASN1156 |
| A | ASN1236 |
| A | MN1501 |
| A | HOH1686 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue DMS A 1504 |
| Chain | Residue |
| A | ALA1115 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 1505 |
| Chain | Residue |
| A | PHE952 |
| A | ALA1108 |
| A | ARG1111 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue DMS A 1506 |
| Chain | Residue |
| A | ARG1027 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 1507 |
| Chain | Residue |
| A | LEU1189 |
| A | GLY1191 |
| A | HOH1644 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 1508 |
| Chain | Residue |
| A | ALA1115 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 163 |
| Details | Domain: {"description":"JmjC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 26 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 13 |
| Details | Compositional bias: {"description":"Pro residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22002947","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
