6G7O

Crystal structure of human alkaline ceramidase 3 (ACER3) at 2.7 Angstrom resolution

Summary for 6G7O

• Entry DOI: 10.2210/pdb6g7o/pdb
• Descriptor: Alkaline ceramidase 3,Soluble cytochrome b562, ZINC ION, SULFATE ION, ... (8 entities in total)
• Functional Keywords: hydrolase, 7tm, zinc binding protein, calcium-binding protein, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 41647.04

Authors

Leyrat, C.,Vasiliauskaite-Brooks, I.,Healey, R.D.,Sounier, R.,Grison, C.,Hoh, F.,Basu, S.,Granier, S. (deposition date: 2018-04-06, release date: 2019-01-02, Last modification date: 2024-01-17)

• Primary citation: Vasiliauskaite-Brooks, I.,Healey, R.D.,Rochaix, P.,Saint-Paul, J.,Sounier, R.,Grison, C.,Waltrich-Augusto, T.,Fortier, M.,Hoh, F.,Saied, E.M.,Arenz, C.,Basu, S.,Leyrat, C.,Granier, S.; Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy.; Nat Commun, 9:5437-5437, 2018; PubMed: 30575723; DOI: 10.1038/s41467-018-07864-w

Experimental method

X-RAY DIFFRACTION (2.7 Å)