6G7O
Crystal structure of human alkaline ceramidase 3 (ACER3) at 2.7 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alkaline ceramidase 3,Soluble cytochrome b562 | polymer | 350 | 40491.1 | 1 | UniProt (Q9NUN7) UniProt (P0ABE7) Pfam (PF05875) Pfam (PF07361) | Homo sapiens (Human) | Alkaline CDase 3,Alkaline dihydroceramidase SB89,Alkaline phytoceramidase,aPHC,Cytochrome b-562 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D, E, F, G... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | I, J, K (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 5 | L (A) | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 1 | Chemie (OLB) | |||
| 6 | M (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | N, O (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 8 | P (A) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A: 2 - 244 (UniProt: Q9NUN7)
A: 245 - 349 (UniProt: P0ABE7)
| PDB | External Database | Details |
|---|---|---|
| Phe 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Trp 251 | Met 29 | conflict |
| Ile 346 | His 124 | conflict |
| Leu 350 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40491.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1156.0 | |
| All* | Total formula weight | 41647.0 |
