6FX7
Crystal structure of in vitro evolved Af1521
Summary for 6FX7
Entry DOI | 10.2210/pdb6fx7/pdb |
Descriptor | [Protein ADP-ribosylglutamate] hydrolase AF_1521, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total) |
Functional Keywords | macro domain, adp-ribose binding, signaling protein |
Biological source | Archaeoglobus fulgidus DSM 4304 |
Total number of polymer chains | 1 |
Total formula weight | 24135.26 |
Authors | Karlberg, T.,Thorsell, A.G.,Nowak, K.,Hottiger, M.O.,Schuler, H. (deposition date: 2018-03-08, release date: 2019-09-25, Last modification date: 2024-05-01) |
Primary citation | Nowak, K.,Rosenthal, F.,Karlberg, T.,Butepage, M.,Thorsell, A.G.,Dreier, B.,Grossmann, J.,Sobek, J.,Imhof, R.,Luscher, B.,Schuler, H.,Pluckthun, A.,Leslie Pedrioli, D.M.,Hottiger, M.O. Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins. Nat Commun, 11:5199-5199, 2020 Cited by PubMed: 33060572DOI: 10.1038/s41467-020-18981-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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