6FX7
Crystal structure of in vitro evolved Af1521
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | polymer | 215 | 23575.9 | 1 | UniProt (O28751) Pfam (PF01661) | Archaeoglobus fulgidus DSM 4304 | |
| 2 | B (A) | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 1 | Chemie (AR6) PubChem (192) PubChem (25113622) PubChem (25113623) PubChem (44415180) PubChem (51051599) PubChem (44144391) PubChem (445794) PubChem (447048) PubChem (89379870) PubChem (33576) PubChem (447165) PubChem (448826) PubChem (91746164) PubChem (9548001) PubChem (9547960) PubChem (122606931) PubChem (122609061) PubChem (10437766) PubChem (174159053) PubChem (140853820) PubChem (146879505) PubChem (162774256) PubChem (162782217) PubChem (163972867) PubChem (173750345) PubChem (173750346) PubChem (175675949) | |||
| 3 | C (A) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 1 - 192 (UniProt: O28751)
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| Gly -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| His -7 | - | expression tag |
| Ile -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Lys -1 | - | expression tag |
| His 0 | - | expression tag |
| Arg 15 | Lys 15 | engineered mutation |
| Glu 35 | Lys 35 | engineered mutation |
| Cys 74 | Tyr 74 | engineered mutation |
| Leu 97 | Phe 97 | engineered mutation |
| Val 103 | Ile 103 | engineered mutation |
| Gly 105 | Ser 105 | engineered mutation |
| Gly 110 | Glu 110 | engineered mutation |
| Arg 145 | Tyr 145 | engineered mutation |
| Asp 162 | Asn 162 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23575.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 559.3 | |
| All* | Total formula weight | 24135.3 |
