6FV9

Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-007

Summary for 6FV9

• Entry DOI: 10.2210/pdb6fv9/pdb
• Related: 6FDI 6FDS 6FDW 6FDX 6FE3 6FE7 6FEB 6FET
• Descriptor: Phosphodiesterase, MAGNESIUM ION, ZINC ION, ... (6 entities in total)
• Functional Keywords: parasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 82811.62

Authors

Singh, A.K.,Brown, D.G. (deposition date: 2018-03-01, release date: 2019-03-20, Last modification date: 2024-01-17)

• Primary citation: Salado, I.G.,Moreno, C.,Sakaine, G.,Singh, A.K.,Blaazer, A.R.,Siderius, M.,Matheeussen, A.,Gul, S.,Maes, L.,Leurs, R.,Brown, D.G.,Augustyns, K.; TbrPDEB1 structure with inhibitor NPD-007; To be published,

Experimental method