6FV9
Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-007
Summary for 6FV9
Entry DOI | 10.2210/pdb6fv9/pdb |
Related | 6FDI 6FDS 6FDW 6FDX 6FE3 6FE7 6FEB 6FET |
Descriptor | Phosphodiesterase, MAGNESIUM ION, ZINC ION, ... (6 entities in total) |
Functional Keywords | parasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 2 |
Total formula weight | 82811.62 |
Authors | Singh, A.K.,Brown, D.G. (deposition date: 2018-03-01, release date: 2019-03-20, Last modification date: 2024-01-17) |
Primary citation | Salado, I.G.,Moreno, C.,Sakaine, G.,Singh, A.K.,Blaazer, A.R.,Siderius, M.,Matheeussen, A.,Gul, S.,Maes, L.,Leurs, R.,Brown, D.G.,Augustyns, K. TbrPDEB1 structure with inhibitor NPD-007 To be published, |
Experimental method |
Structure validation
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