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6FV9

Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-007

Summary for 6FV9
Entry DOI10.2210/pdb6fv9/pdb
Related6FDI 6FDS 6FDW 6FDX 6FE3 6FE7 6FEB 6FET
DescriptorPhosphodiesterase, MAGNESIUM ION, ZINC ION, ... (6 entities in total)
Functional Keywordsparasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness
Biological sourceTrypanosoma brucei
Total number of polymer chains2
Total formula weight82811.62
Authors
Singh, A.K.,Brown, D.G. (deposition date: 2018-03-01, release date: 2019-03-20, Last modification date: 2024-01-17)
Primary citationSalado, I.G.,Moreno, C.,Sakaine, G.,Singh, A.K.,Blaazer, A.R.,Siderius, M.,Matheeussen, A.,Gul, S.,Maes, L.,Leurs, R.,Brown, D.G.,Augustyns, K.
TbrPDEB1 structure with inhibitor NPD-007
To be published,
Experimental method
X-RAY DIFFRACTION (2.48 Å)
Structure validation

217705

건을2024-03-27부터공개중

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