6FUW
Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the PAS AAUAAA motif at 3.1 Angstrom resolution
Replaces: 6FBSSummary for 6FUW
Entry DOI | 10.2210/pdb6fuw/pdb |
EMDB information | 4225 4225 |
Descriptor | Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33, Cleavage and polyadenylation specificity factor subunit 4, ... (5 entities in total) |
Functional Keywords | 3' pre-mrna processing, polyadenylation, cpsf, beta propeller, aauaaa, rna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 232646.51 |
Authors | Clerici, M.,Faini, M.,Jinek, M. (deposition date: 2018-02-28, release date: 2018-03-21, Last modification date: 2024-07-10) |
Primary citation | Clerici, M.,Faini, M.,Muckenfuss, L.M.,Aebersold, R.,Jinek, M. Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex. Nat. Struct. Mol. Biol., 25:135-138, 2018 Cited by PubMed: 29358758DOI: 10.1038/s41594-017-0020-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.07 Å) |
Structure validation
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