6FRD

Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-637

Summary for 6FRD

• Entry DOI: 10.2210/pdb6frd/pdb
• Descriptor: Phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: parasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 82382.22

Authors

Singh, A.K.,Brown, D.G. (deposition date: 2018-02-15, release date: 2019-03-13, Last modification date: 2024-01-17)

• Primary citation: Singh, A.K.,Brown, D.G.; Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-637; To be published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)