Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | HIS673 |
| A | HIS709 |
| A | ASP710 |
| A | ASP822 |
| A | HOH1116 |
| A | HOH1146 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1002 |
| Chain | Residue |
| A | HOH1127 |
| A | HOH1150 |
| A | HOH1172 |
| A | ASP710 |
| A | HOH1116 |
| A | HOH1123 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GAI A 1003 |
| Chain | Residue |
| A | GLY688 |
| A | LYS693 |
| A | CYS893 |
| A | LEU894 |
| A | GLY896 |
| A | HOH1114 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GAI A 1004 |
| Chain | Residue |
| A | LEU753 |
| A | SER754 |
| A | ASP759 |
| A | ASP762 |
| A | ARG769 |
| A | LEU915 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue GAI A 1005 |
| Chain | Residue |
| A | SER639 |
| A | LEU641 |
| A | LYS644 |
| A | TYR686 |
| A | GAI1008 |
| A | HOH1144 |
| B | GLU696 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 1006 |
| Chain | Residue |
| A | TYR686 |
| A | ASN689 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue FMT A 1007 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GAI A 1008 |
| Chain | Residue |
| A | SER639 |
| A | HIS682 |
| A | TYR686 |
| A | GAI1005 |
| B | LYS644 |
| B | GLU696 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 1001 |
| Chain | Residue |
| B | HIS673 |
| B | HIS709 |
| B | ASP710 |
| B | ASP822 |
| B | HOH1114 |
| B | HOH1156 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1002 |
| Chain | Residue |
| B | ASP710 |
| B | HOH1114 |
| B | HOH1137 |
| B | HOH1150 |
| B | HOH1159 |
| B | HOH1165 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue GAI B 1003 |
| Chain | Residue |
| B | GLY688 |
| B | ASN689 |
| B | GLU692 |
| B | LYS693 |
| B | LEU894 |
| B | GLY896 |
| B | HOH1168 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue GAI B 1004 |
| Chain | Residue |
| A | TYR691 |
| B | GLU696 |
| B | HOH1164 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue GAI B 1005 |
| Chain | Residue |
| B | LEU753 |
| B | SER754 |
| B | ASP755 |
| B | PRO756 |
| B | ASP759 |
| B | ASP762 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue E3Q B 1006 |
| Chain | Residue |
| B | MET785 |
| B | ASN825 |
| B | VAL840 |
| B | THR841 |
| B | MET861 |
| B | LEU870 |
| B | GLY873 |
| B | GLN874 |
| B | PHE877 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHmGlnNsF |
| Chain | Residue | Details |
| A | HIS709-PHE720 | |
