6FQY

Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate

6FQY の概要

• エントリーDOI: 10.2210/pdb6fqy/pdb
• 関連するPDBエントリー: 6fqx 6FQY 6FQZ
• 分子名称: 6-phosphogluconate dehydrogenase, decarboxylating, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: plasmodium, complex, substrate, redoxregulation, oxidoreductase
• 由来する生物種: Plasmodium falciparum 3D7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 107722.70

構造登録者

Fritz-Wolf, K.,Haeussler, K.,Reichmann, M.,Rahlfs, S.,Becker, K. (登録日: 2018-02-15, 公開日: 2018-08-22, 最終更新日: 2024-01-17)

• 主引用文献: Haeussler, K.,Fritz-Wolf, K.,Reichmann, M.,Rahlfs, S.,Becker, K.; Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.; J. Mol. Biol., 430:4049-4067, 2018; PubMed: 30098336; DOI: 10.1016/j.jmb.2018.07.030

実験手法

X-RAY DIFFRACTION (2.9 Å)